BPC157 is a peptide that has unique regenerative properties, from increasing collagen synthesis, reducing inflammation, promoting healing and tissue regeneration, protecting organs from toxins and damage, may imporve depression and anxiety, and it may balance blood pressure. It has also been shown to treat ulcers, heal inflammatory bowel disease as well as the upper and lower GI tract and conditions such as leaky gut (increased intestinal permeability) with remarkable efficiency. It has even been shown to heal damaged organs and influence the brain.

What is BPC 157?

BPC157, also known as Body Protection Compound 157 hinting at it therapeutic potential, is synthetic peptide based off of naturally occurring peptides secreted by the gut. [R] . Scientists consider it a blueprint for an entirely new class of organ-protective/healing drugs.

BPC157 is a protein, and a short peptide chain that is present in stomach acid.

BPC 157 promotes muscle and tendon healing by triggering the formation of new blood vessels – a process called angiogenesis (by increasing VEGF). This explains its regenerative potential and why it might also help heal wounds, cuts, and other types of damage in the body [R, R]. In rats, this effect even held true when they were also treated with corticosteroids (steroid drugs like hydrocortisone), which can slow the healing process [R, R, R].

By increasing new blood vessels, it might help with IBD, in which healing of the inflamed gut lining is slow [R].

Additionally, BPC 157 may promote wound and tendon healing by blocking the growth-inhibiting effects of a specific molecule (called 4‐hydroxynonenal) [R]. Specifically, it may help tendons heal by causing tendon cells to make more receptors for growth signaling molecules. This, in turn, allows the tendon cells to grow and move during injury repair, speeding up the process [R, R].

It can also reduce inflammation, which is probably involved in its effects on wounds, ulcers, and tissue protection [R, R]. BPC 157 injections also reduced inflammation in relating to both stomach ulcers and arthritis [R].

BPC 157 has also been proven to influence the activity of neurotransmitters like serotonin and dopamine. In turn, it might help with depression, seizures, pain, and may further promote gut health through this method of action. More research is needed to understand exactly how it works in the brain [R, R, R, R].

Lastly, it can increase the production of nitric oxide (NO), which lowers blood pressure and helps to reduce the effects of high potassium levels [R, R].

Benefits of BPC157

• Increases collagen synthesis [R]
• Decreases inflammation
• Accelerates healing and tissue regeneration (burns [R], corneal injuries[R], fistulas[R, R, R], intestinal anastomosis, liver [R, R], muscle[R, R, R], nerve damage [R], scar tissue [R], spinal cord injury [R], tendons [R], ulcers [R, R])
• Decreases recovery time
• Stimulates the formation of new blood vessels
• Repairs the brain
• Improves depression and anxiety

Potential Side Effects

No side effects have been observed from the use of BPC-157. As it is proangiogenic, it could enhance growth of cancer. [R]

How To Take BPC157

BPC-157 has a systemic effect on the body.

The subcutaneous method is the easiest and least painful because it involves inserting the injection under the skin, preferably in an area as close to the injury or pain-point as possible.

Alternatively, you can inject BPC-157 intramuscularly, which means stabbing the needle right into the muscle. Needless to say, this is a very painful method, especially when you consider that it’s typically done in an area that’s close to the injury as well.

By far the easiest method is to spray the peptide into your mouth. Just make sure to hold the liquid inside your mouth for about 90 to 120 seconds before swallowing.